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Any mutant allele can be classified into one of five types Changes in the dna base pair sequence of the hypomorphic allele may cause one or more of the following, with the gene still. (1) amorph, (2) hypomorph, (3) hypermorph, (4) neomorph, and (5) antimorph
Other articles where leaky mutation is discussed These alleles are sometimes referred to as leaky mutations, because they provide some function, but not complete, normal function For the minute gene, we concluded that the organism needs both copies to have a wild type phenotype
Loss of one copy (an amorphic mutation) produces a dominant visible mutant phenotype
Deletion of the gene is an example of a classic amorphic mutation These alleles are sometimes referred to as leaky mutations. A leaky mutation is a type of mutation that partially impairs a certain characteristic or function in the mutant, rather than eliminating it completely For instance, normal auxotrophic mutants don´t grow at all in the lack of the appropriate medium
However, it is common to find some leaky mutants that grow very slowly in the absence of the appropriate supplements. As you can see, having fut2 gene mutations are very likely to cause a leaky gut, unless it is properly treated But most of the other factors such as other gene mutations (which most people have), an environmental trigger (which are all around us), and getting an underlying infection (which is inevitable if you have leaky gut and/or poor immunity). Mutations in body cells (somatic mutations) cannot do this but can cause cloned abnormalities including cancers
See also frame shift mutation, insertion mutation, inversion mutation, leaky mutation, lethal mutation, missense mutation, point mutation, nonsense mutation.
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